Month: September 2024
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America’s FDA Approves First New Drug for Schizophrenia in Over 30 Years
Thursday America’s Food and Drug Administration approved Cobenfy, “the first new drug to treat people with schizophrenia in more than 30 years,” reports ABC News:
Most schizophrenia medications, broadly known as antipsychotics, work by changing dopamine levels, a brain chemical that affects mood, motivation, and thinking [according to Jelena Kunovac, MD, a board-certified psychiatrist and adjunct assistant professor at the University of Nevada, Las Vegas, in the Department of Psychiatry]. Cobenfy takes a different approach by adjusting acetylcholine, another brain chemical that aids memory, learning and attention, she said. By focusing on acetylcholine instead of dopamine, Cobenfy may reduce schizophrenia symptoms while avoiding common side effects like weight gain, drowsiness and movement disorders, clinical trials suggest. These side effects often become so severe and unpleasant that, in some studies mirroring real-world challenges, many patients stopped treatment within 18 months of starting it.
In clinical trials, only 6% of patients stopped taking Cobenfy due to side effects, noted Dr. Samit Hirawat, chief medical officer at Bristol Myers Squibb. “That’s a significant improvement over the 20-30% seen with older antipsychotic drugs,” he added…
Schizophrenia is a mental health disorder that affects about 24 million people worldwide, or roughly one in 300 people, according to the World Health Organization.
“Studies for additional therapeutic uses, including the treatment of Alzheimer’s disease and bipolar disorder, are also underway.”
Read more of this story at Slashdot.
Thursday America’s Food and Drug Administration approved Cobenfy, “the first new drug to treat people with schizophrenia in more than 30 years,” reports ABC News:
Most schizophrenia medications, broadly known as antipsychotics, work by changing dopamine levels, a brain chemical that affects mood, motivation, and thinking [according to Jelena Kunovac, MD, a board-certified psychiatrist and adjunct assistant professor at the University of Nevada, Las Vegas, in the Department of Psychiatry]. Cobenfy takes a different approach by adjusting acetylcholine, another brain chemical that aids memory, learning and attention, she said. By focusing on acetylcholine instead of dopamine, Cobenfy may reduce schizophrenia symptoms while avoiding common side effects like weight gain, drowsiness and movement disorders, clinical trials suggest. These side effects often become so severe and unpleasant that, in some studies mirroring real-world challenges, many patients stopped treatment within 18 months of starting it.
In clinical trials, only 6% of patients stopped taking Cobenfy due to side effects, noted Dr. Samit Hirawat, chief medical officer at Bristol Myers Squibb. “That’s a significant improvement over the 20-30% seen with older antipsychotic drugs,” he added…
Schizophrenia is a mental health disorder that affects about 24 million people worldwide, or roughly one in 300 people, according to the World Health Organization.
“Studies for additional therapeutic uses, including the treatment of Alzheimer’s disease and bipolar disorder, are also underway.”
Read more of this story at Slashdot.
Amazon Prime Day Sale Is Almost Here. But Don’t Be Quick to Click, Says This CFP
Before you add another item to your cart, read these money tips.
Before you add another item to your cart, read these money tips.
YouTube blocks songs from artists including Adele and Green Day amid licensing negotiations
Songs from popular artists have begun to disappear from YouTube as the platform’s deal with the performing rights organization SESAC (Society of European Stage Authors and Composers) approaches its expiration date. As reported by Variety, certain songs by Adele, Green Day, Bob Dylan, R.E.M., Burna Boy and other artists have been blocked in the US, though their entire catalogs aren’t necessarily affected. Videos that have been pulled, like Adele’s “Rolling in the Deep,” now just show a black screen with the message: “This video contains content from SESAC. It is not available in your country.”
In a statement to Engadget, a YouTube spokesperson said the platform has been in talks with SESAC to renew the deal, but “despite our best efforts, we were unable to reach an equitable agreement before its expiration. We take copyright very seriously and as a result, content represented by SESAC is no longer available on YouTube in the US. We are in active conversations with SESAC and are hoping to reach a new deal as soon as possible.” According to a source that spoke to Variety, however, the deal hasn’t even expired yet — it’ll reportedly terminate sometime next week — and the move on YouTube’s part may be a negotiation tactic. SESAC has not yet released a statement.
This article originally appeared on Engadget at https://www.engadget.com/entertainment/youtube/youtube-blocks-songs-from-artists-including-adele-and-green-day-amid-licensing-negotiations-151741653.html?src=rss
Songs from popular artists have begun to disappear from YouTube as the platform’s deal with the performing rights organization SESAC (Society of European Stage Authors and Composers) approaches its expiration date. As reported by Variety, certain songs by Adele, Green Day, Bob Dylan, R.E.M., Burna Boy and other artists have been blocked in the US, though their entire catalogs aren’t necessarily affected. Videos that have been pulled, like Adele’s “Rolling in the Deep,” now just show a black screen with the message: “This video contains content from SESAC. It is not available in your country.”
In a statement to Engadget, a YouTube spokesperson said the platform has been in talks with SESAC to renew the deal, but “despite our best efforts, we were unable to reach an equitable agreement before its expiration. We take copyright very seriously and as a result, content represented by SESAC is no longer available on YouTube in the US. We are in active conversations with SESAC and are hoping to reach a new deal as soon as possible.” According to a source that spoke to Variety, however, the deal hasn’t even expired yet — it’ll reportedly terminate sometime next week — and the move on YouTube’s part may be a negotiation tactic. SESAC has not yet released a statement.
This article originally appeared on Engadget at https://www.engadget.com/entertainment/youtube/youtube-blocks-songs-from-artists-including-adele-and-green-day-amid-licensing-negotiations-151741653.html?src=rss